TFs	TF description
AR	Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
ARNT	Involved in the induction of several enzymes that participate in xenobiotic metabolism.
ARNT:AHR	The dimer alters transcription of target genes. Involved in the induction of several enzymes that participate in xenobiotic metabolism.
BRCA1	This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor.
CREB1	This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins
ELF5	A member of an epithelium-specific subclass of the Ets transcritpion factor family.
ELK1	The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade.
ELK4	Involved in both transcriptional activation and repression.
EN1	Homeobox-containing genes are thought to have a role in controlling development.
ETS1	The protein encoded by this gene belongs to the ETS family of transcription factors and has been shown to interact with TTRAP, UBE2I and Death associated protein.
FEV	It functions as a transcriptional repressor.
FOXC1	This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. An important regulator of cell viability and resistance to oxidative stress.
FOXL1	FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis.
GATA2	A member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes and play an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages.
GATA3	Plays an important role in endothelial cell biology.
HAND1:TCFE2α	Hand1 belongs to the basic helix-loop-helix family of transcription factors. The Tcfe2a gene encodes the transcription factor E2A, a member of the “class I” a family of basic helix-loop-helix (bHLH) transcription factors (also known simply as “E-proteins”). The transcription factor E2A controls the initiation of B lymphopoiesis.
HIF1α:ARNT	HIF1 is a homodimeric basic helix-loop-helix structure composed of HIF1a, the alpha subunit, and the aryl hydrocarbon receptor nuclear translocator (Arnt), the beta subunit. The protein encoded by HIF1 is a Per-Arnt-Sim (PAS) transcription factor found in mammalian cells growing at low oxygen concentrations. It plays an essential role in cellular and systemic responses to hypoxia.
HLTF	This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.
HNF4α	The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes
INSM1	This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.
KLF4	Transcription factor that can act both as activator and as repressor. Regulates the expression of key transcription factors during embryonic development.
MAFB	The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells.
MAX	The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors
MZF1_1-4	Binds to target promoter DNA and functions as trancription regulator. May be one regulator of transcriptional events during hemopoietic development. Isoforms of this protein have been shown to exist at protein level.
MZF1_1-5-13	Binds to target promoter DNA and functions as trancription regulator. May be one regulator of transcriptional events during hemopoietic development. Isoforms of this protein have been shown to exist at protein level.
NFE2L1:MafG	Nuclear factor erythroid 2-related factor (Nrf2) coordinates the up-regulation of cytoprotective genes via the antioxidant response element (ARE). MafG is a ubiquitously expressed small maf protein that is involved in cell differentiation of erythrocytes. It dimerizes with P45 NF-E2 protein and activates expression of a and b-globin.